Kab lus no yuav tsom mus rau qhov tseem ceeb enzyme pom hauv plab ntawm txhua tus tsiaj, suav nrog tib neeg. Cov ntaub ntawv dav dav txog cov enzyme pepsin, cov ntaub ntawv hais txog nws cov isomers thiab lub luag haujlwm ntawm cov tshuaj hauv cov txheej txheem zom zaub mov yuav raug txiav txim siab.
Saib dav dav
Ua ntej, cia peb kawm seb cov enzymes pepsin yog dab tsi. Qhov no yuav ua rau koj nkag siab tob rau hauv lub ncauj lus nws tus kheej.
Lub pepsin enzyme belongs rau chav kawm proteolytic ntawm hydrolases thiab yog tsim los ntawm lub plab hnyuv, thiab nws lub luag haujlwm tseem ceeb yog rhuav tshem cov proteins los ntawm cov zaub mov mus rau peptides. Pepsin yog ib qho enzyme uas zom cov proteins hauv ib puag ncig acidic. Nws yog tsim los ntawm cov kab mob ntawm txhua tus tsiaj, nrog rau cov tsiaj reptiles, cov neeg sawv cev ntawm cov noog thiab ntau ntses.
Cov enzyme uas nthuav tawm yog cov proteins uas muaj nyob hauv globular, muaj qhov hnyav molecular ntawm kwv yees li 34500. Cov molecule nws tus kheej tau nthuav tawm nyob rau hauv daim ntawv ntawm cov saw hlau polypeptide thiab muaj peb puas thiab plaub caug amino acids. Nws kuj muaj HPO3 thiab peb daim ntawv cog lus disulfide.
Pepsin yog siv dav hauv tshuaj thiab ua cheese. Nyob rau hauv lub chaw soj nstuam, nws yog siv rau lub hom phiaj ntawm kev tshawb fawb ntau ntxiv ntawm cov protein sib txuas, uas yog, cov qauv ntawm cov protein. Pepsin muaj ib tug natural inhibitor - pepstatin.
ntau yam enzyme
Pepsin muaj kaum ob isoforms. Qhov sib txawv ntawm tag nrho cov pepsin isomers yog nyob rau hauv electrophoretic motor peev xwm, inactivation tej yam kev mob, thiab proteolytic kev ua si. Pepsin code - KF 3. 4. 23. 1.
Tib neeg lub plab kua txiv muaj xya hom pepsin, thiab tsib ntawm lawv txawv ntawm qee qhov zoo:
1. Qhov tseeb, pepsin (A) muaj qhov ua haujlwm siab tshaj plaws hauv nruab nrab pH=1.9, thiab nrog nce mus rau 6 nws yog inactivated.
2. Pepsin 2 (B) yog qhov ua haujlwm siab tshaj plaws hauv nruab nrab pH=2.1.
3. Hom 3 qhia qhov siab tshaj plaws ntawm kev ua haujlwm ntawm pH=2.4–2.8.
4. Hom 5, tseem hu ua gastrixin, muaj qib siab tshaj plaws ntawm kev ua haujlwm ntawm pH ntawm 2.8–3.4. 5. Hom 7 ntawm pH=3.3-3.9 muaj qhov ua haujlwm siab tshaj plaws.
Qhov tseem ceeb ntawm cov enzyme hauv kev zom zaub mov
Pepsin yog zais los ntawm cov qog nqaij hlav hauv daim ntawv deactivated (pepsinogen), thiab kev ua haujlwm ntawm cov enzyme nws tus kheej yog qhib los ntawm hydrochloric acid. Nyob rau hauv nws tus cwj pwm, nws mus rau hauv ib tug workable daim ntawv. Ib qho yuav tsum tau ua ua ntej rau kev ua haujlwm ntawm pepsin enzyme yog qhov muaj cov kua qaub ib puag ncig, uas yog vim li cas thaum pepsin nkag mus rau hauv duodenum, nws poob nws txoj haujlwm, txij li ib puag ncig hauv cov hnyuv yog alkaline. Lub enzyme pepsin tuav ib lub luag haujlwm tseem ceeb hauv kev zom zaub mov ntawm tag nrho cov chav kawm.tsiaj txhu, thiab tshwj xeeb yog tib neeg. Cov tshuaj no rhuav tshem cov zaub mov protein rau hauv cov saw me peptide thiab cov amino acids.
Txiv neej thiab poj niam muaj ntau theem ntawm cov enzyme no. Cov txiv neej secrete txog nees nkaum mus rau peb caug grams pepsin ib teev, thaum cov poj niam muaj nees nkaum mus rau peb caug feem pua tsawg. Lub hlwb basal, qhov chaw ntawm pepsin ntau lawm, zais nws hauv daim ntawv tsis ua haujlwm ntawm pepsinogen. Tom qab cleavage ntawm ib tug npaum li cas ntawm peptides los ntawm N-terminus, pepsinogen kis mus rau hauv nws active daim ntawv. Hydrochloric acid ua raws li cov catalyst hauv cov tshuaj hloov pauv tshuaj. Pepsin muaj cov khoom protease thiab peptidase thiab muaj lub luag haujlwm rau kev sib cais ntawm cov proteins.
Tshuaj
Hauv tshuaj, pepsin tau siv dav los ua tshuaj rau qee cov kab mob cuam tshuam nrog kev tsis muaj cov enzyme no hauv tus neeg mob lub plab. Lub rennet enzyme pepsin tau txais los ntawm cov mucous daim nyias nyias ntawm lub plab. Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, teem nyob rau hauv hlwv, nrog ib tug admixture ntawm acidin los yog nyob rau hauv daim ntawv ntawm hmoov. Pepsin kuj yog ib feem ntawm qee cov tshuaj ua ke. Nws muaj ATC code A09AA03. Ib qho piv txwv ntawm cov kab mob uas muaj cov tshuaj pepsin yog tus kab mob Menetrier.
Nqaij pepsin yog…
Beef rennet pepsin yog ib qho ntawm cov paub zoo thiab feem ntau siv cov ntaub ntawv no. Lub enzyme nws tus kheej yog tsim nyob rau hauv plaub lub plab ntawm tus nyuj. Cov tshuaj siv hauv kev tsim khoom yog tsim los ntawm ob lub enzymes:pepsin thiab chymosin nyob rau hauv natural proportions. Rennet yog siv los ua cheese, thiab nws lub luag haujlwm tseem ceeb yog tsim cov kua mis thiab kev koom tes hauv cov txheej txheem ntawm kev loj hlob ntawm cheese thiab curd khoom.
Nqaij pepsin yog muab rho tawm los ntawm lub plab ntawm nyuj thiab hauv kev tsim cov khoom muag, mus txog ob theem ntawm kev ua kom huv ntawm cov enzyme los ntawm cov rog thiab impurities uas yog insoluble. Cov txheej txheem ntawm kev ua nqaij nyug pepsin mus dhau ntau theem: txheej txheem rho tawm, s alting tawm thiab khov kom qhuav.
Lwm daim ntawv thov
Cov enzyme pepsin ntxiv rau cov kua qaub. Nws kuj tseem siv tau los ua cheese. Lub rennet enzyme pepsin ua ke nrog chymosin tsim tib lub enzyme siv los curdle mis nyuj.
Cov txheej txheem ntawm cov mis nyuj yog hu ua nws cov protein coagulation, uas yog casein, nrog rau kev tsim cov kua mis raws li gel. Casein muaj cov qauv tshwj xeeb, thiab tsuas yog ib daim ntawv cog lus peptide yog lub luag haujlwm rau hom enzymatic ntawm cov protein folding. Lub complex ntawm pepsin nrog chymosin yog lub luag haujlwm rau kev rhuav tshem cov ntawv cog lus thiab ua rau mis nyuj curdling.
Zoo kawg
Summarizing, peb tuaj yeem hais tias cov tshuaj lom neeg lom neeg no yog ib qho tseem ceeb tshaj plaws enzymes koom nrog hauv kev zom zaub mov hauv plab ntawm cov neeg sawv cev ntawm ntau pawg ntawm cov tsiaj nyob. Hauv kev tsim thiab tshuaj, cov tshuaj yog siv los ua tshuaj thiabntxiv rau rennet rau kev tsim cov khoom siv mis nyuj thiab cheese.
