Dab tsi yog cov tshuaj tiv thaiv zoo li disulfiram? Vim li cas lawv thiaj txaus ntshai?

Cov txheej txheem:

Dab tsi yog cov tshuaj tiv thaiv zoo li disulfiram? Vim li cas lawv thiaj txaus ntshai?
Dab tsi yog cov tshuaj tiv thaiv zoo li disulfiram? Vim li cas lawv thiaj txaus ntshai?
Anonim

Raws li ib txwm muaj, thaum nws nkag mus rau hauv lub cev, cawv sai sai decomposes rau hauv metabolites (cov khoom tsis muaj tshuaj lom metabolic). Txawm li cas los xij, raws li kev noj ntau yam tshuaj, kev ua txhaum cai tshwm sim hauv cov txheej txheem ntawm kev lwj. Nyob rau tib lub sij hawm, tus nqi ntawm chem. cov tshuaj tiv thaiv yuav nyob ntawm seb qhov ntau npaum li cas ntawm cov tshuaj thiab tus nqi ntawm cov cawv. Cov tshuaj tua kab mob yuav tsum raug suav hais tias yog cov tshuaj uas ua rau muaj kev phom sij tshaj plaws. Thaum haus cawv siv los ntawm kev kho mob, muaj qhov tshwm sim loj heev. Cov no suav nrog cov tshuaj tiv thaiv zoo li disulfiram. Nrog rau txoj kev loj hlob ntawm cov teebmeem no, cov neeg mob loj tuaj, nrog rau lwm cov tsos mob, kev aversion rau cov khoom uas muaj cawv.

tshuaj tiv thaiv tus nqi
tshuaj tiv thaiv tus nqi

Tshuaj uas ua rau muaj kev cuam tshuam zoo li disulfiram

txhais tau tias "Trichopol" muaj cov tshuaj tua kab mob thiab cov tshuaj tiv thaiv kab mob. Thaum ua ke nrog cawv, cov tshuaj ua rau cov neeg mob hnyav, uas muaj cov tshuaj disulfiram zoo li tshwm sim. Cov khoom no tso cai rau kev siv cov tshuaj rau kev kho mob ntawm cov neeg haus dej haus cawv. Heev feem ntau, ib tug tshuaj xws li"Amoxicillin". Cov tshuaj no tuaj yeem ua rau ua pa nyuaj, thiab cawv tuaj yeem ua rau muaj kev cuam tshuam ntawm kev ua pa ntawm lub hlwb. Hauv qhov no, kev sib xyaw ua ke ntawm "Amoxicillin" thiab cawv ua rau muaj feem yuav tuag rau cov neeg uas qaug cawv. Muaj cov tshuaj uas tau sau tshwj xeeb los ua kom muaj kev cuam tshuam zoo li disulfiram. Cov no yog cov tshuaj xws li Esperal, Antabuse thiab lwm yam. Thaum lawv noj, ib qho enzyme tshwj xeeb raug rhuav tshem. Lub npe ntawm cov tshuaj tiv thaiv los ntawm cov tshuaj "Disulfiram". Cov tshuaj no kuj yog, nrog rau lwm cov tshuaj zoo sib xws, siv los kho kev haus cawv hauv daim ntawv ntev. Cov mob uas tshwm sim thaum noj nws yog hu ua disulfiram-cawv, yog tias muaj kev phiv los ntawm lwm yam tshuaj, nws hu ua disulfiram-zoo li.

Cov tshuaj tiv thaiv zoo li disulfiram
Cov tshuaj tiv thaiv zoo li disulfiram

Yog vim li cas rau kev phiv

Txoj kev loj hlob ntawm lub xeev yog tshwm sim los ntawm kev sib txuam hauv lub cev ntawm cov khoom ntawm kev tawg ntawm ethanol - acetaldehyde. Cov tshuaj no yog tshuaj lom heev. Nyob rau hauv ib txwm muaj xwm txheej, cov tshuaj yog neutralized nyob rau hauv tus ntawm ib tug xov tooj ntawm enzymes (aldehyde dehydrogenase thiab lwm yam). Qee cov tshuaj muaj peev xwm inhibit qhov kev ua ntawm cov ntsiab lus no. Yog li ntawd, acetaldehyde accumulates nyob rau hauv lub cev, uas yog nrog los ntawm ib tug xov tooj ntawm cov yam ntxwv tsos mob. Nrog rau qhov no, cov tshuaj thaiv qhov kev ua ntawm ntau lwm cov enzymes. Qhov no, nyob rau hauv lem, provokes ib tug txo nyob rau hauv cov theem ntawm norepinephrine nyob rau hauv lub paj hlwb thiab ua txhaum cai.nws txoj kev sib raug zoo nrog dopamine. Raws li qhov tshwm sim, cov tshuaj tiv thaiv zoo li disulfiram tau txhim kho ntau dua. Cov kws tshaj lij tau sau tseg tias tus mob no muaj tus cwj pwm ntev ntev. Hauv qhov no, cov kws kho mob tsis pom zoo kom haus cawv tom qab ua tiav kev kho mob rau qee lub sijhawm. Nws yuav tsum tau hais tias cov kev mob tshwm sim ntawm kev haus cawv thaum lub sijhawm kho mob hnyav heev, tsim kom muaj kev tsis txaus siab rau cawv.

Cov tsos mob ntawm cov tshuaj tiv thaiv zoo li disulfiram

Thaum muaj kev phiv tshwm sim, tus neeg mob pib hnov mob thiab liab ntawm lub cev thiab ib ncig ntawm lub ntsej muag. Tsis tas li ntawd, lub siab txo qis, ua pa nyuaj, thiab lub plawv dhia nce. Cov neeg mob muaj lub siab nruj ntawm lub hauv siab, ntshai. Tus mob yog nrog los ntawm kev xav txog kev tuag, xeev siab, ntuav. Qhov kev pheej hmoo ntawm kev tsis sib haum xeeb ntawm lub paj hlwb nce. Nrog rau qhov nce ntawm cov cawv, qhov kev siv thiab qhov hnyav ntawm cov tshuaj disulfiram zoo li cov tshuaj tiv thaiv nce. Qee qhov xwm txheej, kev tawg tuaj yeem tshwm sim - qhov txo qis hauv siab nrog kev tsis nco qab.

Cov tshuaj tiv thaiv zoo li disulfiram
Cov tshuaj tiv thaiv zoo li disulfiram

Kev kho mob ntawm cov neeg mob uas haus dej cawv ntev ntev

keeb kwm ntawm kev siv tshuaj "Disulfiram" txhawm rau tshem tawm kev cia siab ntawm cawv pib nrog ib qho kev soj ntsuam zoo. Ntawm ib lub tuam txhab roj hmab, kev haus cawv los ntawm cov neeg ua haujlwm tau poob qis heev. Thaum lub sij hawm txoj kev tshawb no, nws tau pom tias qhov ua rau yog cov tshuaj disulfiram, uas tsuas yog siv nyob rau hauv kev tsim khoom.cov khoom siv roj hmab. Qhov kev tshawb pom no coj mus rau qhov tseeb tias qhov sib xyaw pib siv rau kev kho mob. Ib me ntsis tom qab, cov kws tshaj lij tau sau tseg tias ntau cov tshuaj kuj ua rau muaj kev cuam tshuam zoo li disulfiram. Qee cov tshuaj tau pib tshwj xeeb rau cov neeg haus cawv ntev. Piv txwv li, cov kws kho mob feem ntau sau lawv cov tshuaj "Trichopol". Cov tshuaj no ua ib feem ntawm kev kho mob nyuaj los ntawm qee tus kws kho mob tau sau tseg tam sim no. Nws raug nquahu kom haus nws hauv cov chav kawm ntawm 250 mg 2 rubles / hnub. Kev kho mob yog ua ob zaug hauv ib xyoos. Qee qhov xwm txheej, cov tshuaj kuj tau sau tseg rau lub sijhawm ntev - mus txog ob peb lub hlis.

Cov tshuaj tiv thaiv zoo li disulfiram
Cov tshuaj tiv thaiv zoo li disulfiram

cov lus qhia tshwj xeeb rau qee yam tshuaj

Cov neeg uas tsis raug kev txom nyem los ntawm kev quav cawv, cov kws kho mob pom zoo kom tsis txhob muab cov tshuaj sib xyaw nrog cov dej cawv. Nws yog ib qho tseem ceeb tshwj xeeb uas yuav tsum tau ua raws li kev ceev faj thaum tau txais cov tshuaj tua kab mob. Nws yuav tsum nco ntsoov tias kev siv tshuaj sib xyaw ua ke thiab ethanol, ntxiv rau kev txhim kho cov tshuaj tiv thaiv zoo li disulfiram, ua rau muaj kev pheej hmoo ntawm kev puas tsuaj rau lub siab, ua txhaum ntawm txoj haujlwm tseem ceeb ntawm nws txoj haujlwm tseem ceeb tshaj plaws (filtration thiab detoxification). Tsis tas li ntawd, qhov kev siv ntawm cov kev mob tshwm sim uas provoke tshuaj tua kab mob, tshuaj uas cuam tshuam rau lub paj hlwb thiab lwm yam tshuaj muaj zog. Cov tshuaj lom metabolites, uas yog tsim thaum cov tshuaj thiab cawv sib xyaw ua ke, tuaj yeem hloov cov nyhuv ntawm cov tshuaj noj. Qhov no, dhau los, ua rau muaj qhov tshwm sim loj heev, qee zaum ua rau tuag.

Ceeb toom hauv kev kho mob quav cawv

Rau cov neeg quav cawv, ntau yam tshuaj tau tsim los pab tshem tawm qhov kev quav yeeb quav tshuaj no.

Cov tshuaj tiv thaiv zoo li disulfiram
Cov tshuaj tiv thaiv zoo li disulfiram

Cov kws tshaj lij ceeb toom koj tias noj tshuaj twg yuav tsum tau pom zoo nrog tus kws kho mob. Tsis yog txhua tus neeg haus cawv yeem yeem pom zoo rau kev kho mob. Cov neeg mob zoo li no yuav tsum tau txais kev pab cuam lub hlwb thawj zaug. Ib tug neeg raug kev quav dej caw yuav tsum tau paub txog kev kho mob tsis tu ncua. Nyob rau hauv tsis muaj cov ntaub ntawv yuav tsum tau koj muab tshuaj uas ua rau ib tug aversion rau cawv yam tsis paub nws! Xws li "kev kho mob" tuaj yeem tsis tsuas yog ua tsis tau zoo, tab sis kuj ua rau mob hnyav, txaus ntshai nyob rau qee kis, qhov tshwm sim.

Pom zoo: